Organization type Private sector Province Alberta Challenges Addressing the spread of the Covid-19 and future emerging diseases is to prevent the spread of diseases including airborne pathways and surface contamination. Our technology can curtail transmission of infectious diseases in all buildings particularly in health care facilities. We have improved the efficacy of our photocatalytic oxidation of volatile organic compounds by about 300% beyond our US and Chinese patents. Independent testing by the Chinese Central Government and laboratories substantiated our previous performances. The germicidal properties of our technology achieved 87.74% to 99.21% kill rate for bacteria, moulds, and viruses with a single pass at 20 l/s to 50 l/s. We have invested about half million dollars, not counting sweat equity and we just added another $100k for this spring. It is almost ready for commercialization. We have never sought funding before but we now need assistance to advance our prototypes and conduct final laboratory testing, so that it can be manufactured this year to address the spread of COVID-19 and other emerging diseases. Expertise needed Several directors have over 30 years teaching, research and publication in peer reviewed journals and professional reports. Our directors are air quality consultants qualified by Alberta Health, with PhD and MBA, including an Emeritus Professor, and qualified as expert witness on air contaminants and healthy buildings for over 50 cases. We have manufactured and continued development of air purification technologies and continued to increase its efficacy. Our initial approach is for removal of VOC’S including dioxins and furans (a carcinogen) in municipal garbage incinerators, and odour control and disinfection of household garbage collection facilities. To this end we have a MOU with a large Chinese company to purchase our core technology. However, the verified germicidal properties is also one of the answers to the COVID-19 pandemic. Keywords -
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Organization type Private sector Province Ontario Challenges Use our [name redacted] platform to help Vocational Services Organizations offer their marginalized clients find extra work in what is now the most challenging times to find work. Expertise needed How can [name redacted] be used to replace employment? What are the benefits of [name redacted] to marginalized Canadians? How can we structure our platform to provide the Vocational Organizations a feedback card after a [name redacted] is complete to help mentor their client? What are easy skill development videos and questionnaires that we can integrate into our technology to help enhance skills before a job? How can we roll out this technology to help more marginalized Canadians and the Organizations they are working with? Keywords -
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Organization type Private sector Province Quebec Challenges We have received a Site Licence from Health Canada to manufacture a hand disinfectant, and we will need an expert to validate both the formula and the manufacturing process. Expertise needed Tests on the various formulas for various types of disinfectants. Validation of formulas. Determination of adjustments to be made to the manufacturing process. Keywords -
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Organization type Private sector Province British Columbia Challenges Complete research and development of multimodal biosensors for measuring inflammatory responses from viruses like the COVID-19 and or bacterial invasion in lymph nodes or remote physical examination of patients. Expertise needed Software and hardware engineers to complete building and testing prior to manufacturing. Keywords -
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Organization type Private sector Province New Brunswick Challenges Supply a type of equipment that provides an alternative to negative-pressure rooms when they cannot be built quickly enough or in sufficient number. This equipment would sanitize the air where necessary, including in hospital rooms and in bedrooms of Covid-19 patients being treated at home, as well as in detention facilities, hospices, grocery-store aisles, and anywhere else where both healthy people and people who are carriers of the COVID-19 virus may pass. Expertise needed We need epidemiologists who are familiar with the COVID-19 virus and its presence in the ambient air and who can verify whether this equipment sanitizes the air by destroying this virus effectively. Keywords -
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Organization type Private sector Province Quebec Challenges Demonstration of efficacy of intranasal probiotic treatment in preventing development of or in mitigating severity of COVID-19 infection. Expertise needed We need to perform a clinical trial in patients with mild to moderate COVID-19 infection to document impact on outcome. Keywords -
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Organization type Private sector Province British Columbia Challenges We are a start-up medical device company refocusing our efforts towards the COVID-19 crisis. As a team of physicians, we have identified a significant clinical need of remote wearable vital sign monitoring technology. We are hoping to develop a wearable sensor that can track the big 5 vital signs (BP, HR, RR, SpO2, Temp) in real time and transmit the data to clinicians to assist in remote/tele medicine. Ideally, the device should be cost-effective <100$, easy to use, wearable, battery operated, and able to transmit real time data to a network through a mobile device. Plethysmography (PPG) has been identified as the most innovative and non-invasive method. However, significant design, cost, and clinical validity issues remain to be solved. Expertise needed Biomedical engineering, Mechatronics engineering, Wearable technologies, Sensor technology, Wireless/IoT technology, Plethysmography research. Looking for labs/academics with engineering expertise and wearable sensor technologies to help us develop this device. Keywords Biomedical engineering, mobile vital signs monitor
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Organization type Private sector Province Quebec Challenges To design and build a prototype ventilation unit that is portable with filtration and UV-C and ozone generator to be used for sterilization of enclosed areas, such as vehicles, ambulances and mass transit units. Remote telemetry and sensors to capture live data and adjust parameters with AI. Expertise needed Engineering design for hardware, software and AI metrics for testing performance using NDIR scanning of surfaces and ozone concentrations, temperature, and relative humidity. Keywords ozone sterilization of COVID-19 tainted surfaces
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Organization type Private sector Province British Columbia Challenges • Development and evaluation of bioinformatics processes to accurately identify SARS-CoV-2 in nanopore metagenomic data<br>• Advancement of automated processes to generate phylogenetic trees of SARS-CoV-2 from nanopore metagenomic data<br>• Application and assessment of SARS-CoV-2 tools on benchmark and real metagenomic data from COVID patients<br>• Development of GUI installable software to perform real-time metagenomic analysis during nanopore sequencing<br>• Integration of ReadUntil technology into GUI for selective sequencing of SARS-CoV-2 or host depletion Expertise needed We are in need of bioinformatics expertise and research capacity to develop and validate our algorithms for nanopore metagenomics, phylogenetics and other pathogen-specific analyses. The partner should have experience with microbial genomic/metagenomic data analysis. Experience with nanopore sequencers and bioinformatic workflow orchestrators (eg. Nextflow) is a plus. Additionally, we are seeking computer scientists and software engineers for development of our offline GUI sequencing package. This partner should have extensive experience with Microsoft Windows and/or macOS software development. Keywords bioinformatics, metagenomics, nanopore
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Organization type Private sector Province Ontario Challenges My organization is looking to provide a social distancing video surveillance algorithm to gather statistics of where the most non-compliant areas are and allow our property owners and governments to set up signs and barriers more effectively. We are also exploring the sending of an alert upon certain criteria that is deemed critical. Expertise needed We have been in the AI, Machine Learning space for the last 3 years as a company and have employed 4 PhDs who had 15+ years of expertise in machine vision. We are an expert in building video detection technologies, as evident by our current platform that takes in more than 500 live feeds to detect anomaly for construction sites. We have been granted various CRD, Mitacs, and IRAP projects in the past. We have also attracted $11M USD venture capital from Silicon Valley. We are a Canadian Corporation, where all of the R&D is done in Canada. The US is our sales and distribution office. Keywords social distancing, AI, video
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Organization type Private Sector Province Ontario Challenges [Name redacted], which is based on the organization’s existing software platform, would provide Canadian citizens with an autonomous personal directory of COVID-19 peer material from all levels of government supported organizations (research, public health and policy makers), in one convenient secure location, driven by ML/AI processes to target content at the user to improve awareness, engagement and knowledge, while collecting big healthcare data. The challenge that most Canadians have when accessing large content pools, is personalizing, collecting and storing the content to meet their needs so that it is readily available. The organization proposes to deploy an autonomous personalized healthcare content directory system for each registered user within the [name redacted] healthcare community. [Name redacted] would give users the option to build a personalized home page to hold all the COVID-19 healthcare content within the [info redacted] community, conversations, and connections that are pertinent and relevant to their personal needs. The [name redacted] would have portals and categories of validated evidence-based healthcare content related to COVID-19 and other contagious disease states, and would promote health improvement (peer research and best practices) in a wide range of topics to appeal to patients, clinicians, practitioners, researchers and medical doctors. As the registered user navigates each portal, we would permit them to activate the [name redacted] feature, which would enable manual and autonomous processes (machine learning processes) to build their personalized healthcare directory. The goal is to develop a completely autonomous healthcare community platform populated with validated evidence-based healthcare content related to COVID-19 and other contagious disease states for expert peers, patients and clinicians, which is driven by supervised and unsupervised machine learning processes. Expertise needed • Analyze and verify that the autonomous personalized content data profile is correct on the site, and matches the user’s dynamic profile, autonomously finding readers, presenting a personalized content view, and analyzing results to improve targeting of current and future articles <br>• Review the code actions based on data analysis to curate and recommend content accurately<br>• Analyze and verify that the autonomous processes in [name redacted], which change the landing page and content layout based on the viewer profile, permits the user to interact with the content and provide feedback to be used to further tune the content layout. <br>• Analyze and verify that the autonomous process to build continuous flow content pages in [name redacted], which is based on business logic, is correct <br>• Review and verify that the [name redacted] code actions based on data analysis to cluster content accurately and review feedback from the viewer to confirm positive user engagement, and refine content clusters when necessary to increase engagement<br>• Analyze and verify that the autonomous clustering of content is correct and meets or exceeds the success parameters<br>• Analyze the new synthesized code and confirm through managed processes that the new code is valid<br>• Analyze and research that the autonomous processes designed to build peers dynamic, based on abstracts, comments, articles, areas of interest, and use big data to create awareness and promote engagement with peers, and display a unique appearance to each peer viewer<br>• Analyze and verify that the autonomous processes, which will adjust the [name redacted] content based on the profile of each unique viewer to maximize engagement and interaction, is generating positive engagement with the viewer expertise required:<br>- data scientists - ML/AI engineers<br>- enterprise SaaS engineers<br>- human computer interaction (UI/UX) analysts<br>- cyber security engineers<br>- mobile app developers Keywords autonomous, healthcare, communities
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Organization type Private Sector Province Quebec Challenges 1- Early detection of suspected COVID-19 symptomatic cases: Early detection of flu-like symptoms such as high heart rate, fever, cough detection and increased sleep duration will decrease delays in COVID-19 diagnosis, thus enabling clinicians to target robust isolation measures to high-probability cases and preventing further community spread. <br>2- Monitoring of positively diagnosed outpatients: Early detection of deteriorating vital signs such as hypotension, low blood oxygen saturation and recurring fever can help improve patient care by reducing delays due to complications management. <br>3- Demonstrate the applicability of our proprietary wrist smart device using AI and machine learning algorithms to remotely monitor positively diagnosed COVID-19 outpatients by continuously measuring heart rate, blood oxygen saturation, body temperature, sleep analysis and activity. Expertise needed Access to COVID-19 patients in ICU, after ICU and when released. Skilled nurses and doctors, artificial intelligence, machine learning, and data science expertise. Keywords health management, vital sign, wearable
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Organization type Private Sector Province Alberta Challenges Our company's number one priority at this time is to develop a point of need system for testing COVID-19. This should be a portable system that does not require a trained operator for performing the test. The primary component of the system is a microfluidic chip in transparent material. The testing system utilizes fluorescent polystyrene microspheres, and the test is based on the measurement of fluorescent intensity. We would like to develop this system to a working prototype ready for testing the live virus and we want to do this in a very short period of time. Expertise needed In our start-up company we are a group of engineers, and we have limited knowledge in areas such as chemistry or, more specifically, biochemistry. We need the expertise of someone who could coat fluorescent beads with antibodies and proteins, for example. Keywords lab-on-a-chip, microfluidics, flow-cytometry
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Organization type Private Sector Province Alberta Challenges As an optometrist my objectives would clearly focus on the effects of COVID-19 on ocular health, vision-threatening complications and providing a treatment plan of action. Expertise needed My research would focus on key ocular structures that affect vision; specifically, the effect of COVID-19 on the cornea. I would have to dive into the layers of the cornea and see how the virus directly and indirectly affects the different layers of the cornea. Keywords optometry, health, challenge is new opportunity
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Organization type Private Sector Province Ontario Challenges How we move about in our communities—where we go and how often—greatly affects the spread of COVID-19. In an effort to help researchers and governments combat the pandemic, TELUS has launched its <a href="https://www.telus.com/en/about/covid-19-updates/privacy-statement" target="_blank">Data for Good</a> program until July 1, 2020. TELUS' network mobility data is strongly de-identified, aggregated and extrapolated to market share in order to protect the privacy of its 9 million subscribers (see<a href="https://www.telus.com/en/about/privacy/data-analytics" target="_blank"> here</a>). This data can be used to view movement at the population level, and is vital to help researchers understand trends in population movement and predict the spread of the disease, as well as to support governments in making informed decisions. For more information about the TELUS COVID-19 data sharing program, please contact <a href="mailto:Joe.rowsell@telus.com" target="_blank">Joe Rowsell</a>, Regulatory Affairs Director. Expertise needed -
Keywords data, trends
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Organization type Private Sector Province British Columbia Challenges [Name redacted] is an environmental analysis laboratory looking to participate in the study to develop wastewater-based epidemiology for SARS-CoV-2. We have spoken with wastewater professionals at several municipalities who are interested in the potential this method has to offer. At this point we are not set up to analyze via qPCR but have reached out to government about funding and collaboration. We have a large network of WWTPs that we work with and test samples for a variety of water quality parameters, which will help with studying the matrix in which COVID-19 is found. Our goal here is to partner with researchers who are interested in optimizing the methodology in collaboration with some of the groups looking at this problem in other countries. Our objective is to develop a standard method for implementation country-wide that provides reliable testing to all communities. Expertise needed We would be looking for experience with RNA extraction from environmental samples for the purpose of analysis via qPCR. Method development related to qPCR. The study will need to look at a number of variables, including: - persistence of RNA in samples <br>- how the background chemistry impacts viral load <br>- optimal primer set <br>- quality controls <br>- best sample collection practices and extraction technique Keywords wastewater, environmental, laboratory
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Organization type Private Sector Province Alberta Challenges Currently working on a project on using complete contingent plans to (1) coordinate, optimize, and automate resource allocation and management for coronavirus and (2) safely reopen in US, which can be modified to combat challenges in Canada. Benefits: <br>(1) Facilitate stronger state-fed/region communications <br>(2) Result in more optimal resource allocations and RI suppression <br>(3) Lead to quicker responses <br>Fed-State Resource Management Concept Demo Software and State Reopening Concept Demo Software [concept demo software are available once connection is made]. Expertise needed Software development expertise. Keywords complete, contingent, plans
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Organization type Private Sector Province Ontario Challenges We would like to manufacture medical grade non-contact thermometers that wirelessly transmit collected data for medical professionals to examine. The data analysis may provide insight as to the temperature ranges for COVID-19. This may also help identify when and where infected people are, so they can get medical attention if necessary. The expectation is that these thermometers will allow for the transition to a regular working economy and help to reduce transmission; if someone is within the COVID-19 temperature range, then they must remain in quarantine rather than return to work. Expertise needed I need a medical professional to review the idea and let us know if they feel this data and use will assist in fighting COVID-19 outbreak. We would also like to know any insights or special data points that will be valuable to include and generate more impact. Thank you Keywords temperature, data, collection
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Organization type Not-for-profit Province Ontario Challenges Canadian non-profit [name redacted] is currently using health technology to help fight COVID-19 across North America (with the help from our partners [info redacted]), and will soon be expanding our aid to Asia and Europe in the coming weeks. Accelerate COVID-19 research, and take care of your family with free, at-home health monitoring. In an effort to aid in the fight against the COVID-19 global pandemic, non-profit [name redacted] has just launched [name redacted], a free connected self-monitoring solution that allows families to proactively monitor their health together using affordable wearable devices. This platform allows people to proactively monitor key vital signs for COVID-19—such as SpO2, heart rate, body temperature, etc.—on their mobile phone in real-time, using widely available devices. [Info redacted]. In providing people with the ability to have selected friends and family monitor their health status, we can help provide peace of mind to families who are feeling anxious, and worried about the health of their loved ones. For those who are still able to get appointments with doctors, [name redacted] also provides them with the ability to share their health data with clinicians, allowing for effective remote monitoring and swift intervention when necessary. In tandem, [name redacted] has also launched one of the largest open COVID-19 databanks in the world, open to all health researchers to accelerate research into COVID-19. Everyone using [name redacted] services will have the option to donate their data to the databank, providing researchers with access to thousands of research-quality, real-world physiological datasets. Researchers from across North America have already committed to joining the efforts in analyzing this data. Expertise needed Hundreds of researchers from across North America have already signed up to have access to our COVID-19 databank. As a Canadian non-profit, we are hoping that Canadian universities and researchers will also support this initiative. Our goal is to provide help and assistance to those impacted by COVID-19. Please help us raise awareness of this initiative amongst your networks, and if you think you or your university may be interested in potentially collaborating with [name redacted], and joining us on our fight against the COVID-19 pandemic, please do not hesitate to reach out. Keywords COVID-19, databank, monitoring
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Organization type Not-for-profit Province British Columbia Challenges • Validate a novel, patent pending gravity powered ventilator for COVID-19 and general respiratory failure patients, which we have prototyped<br>• Map developing world requirements for said ventilator and entry point hurdles, and then proceed to move past them <br>• Validate novel noninvasive positive pressure aerosol mitigating patient-side respiratory support device, which we have prototyped <br>• Continue to iterate and validate novel provider-side bidirectional aerosol mitigating PPE device we have prototypes for Expertise needed • Expertise in not only province-wide, but Canada-wide and worldwide epidemiology of COVID-19, regulatory requirements, and design and distribution of medical equipment <br>• Expertise in business development <br>• Established manufacturing partnerships and go-to-market strategy with different products in different locations in Canada and globally <br>• Biomedical engineering expertise in medical device testing for ISO standards <br>• Infectious disease expertise in testing NIPPV and PPE devices to standards <br>• Expertise in design for manufacturing Keywords low-cost ventilators, open-source designs, PPE
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Organization type Private Sector Province Quebec Challenges The organization was established in 2003 by former Merck’s Senior Researcher [info redacted]. Over the years, the organization attracted several brilliant scientists, including biotechnologists, microbiologists and geneticists. Such a fusion of experts resulted in the development of a revolutionary drug family called [name redacted], which works by precise targeting and the subsequent destruction of the genome of a pathogen, and this includes SARS-CoV-2 (COVID-19). [Name redacted] is an interdisciplinary invention—it includes polymer science, molecular biology, drug delivery, nanotechnology and genetics. The drug is engineered in the form of an active system packed into a polysaccharide nanoparticle. In such a form the active system can be delivered through the blood system into cells of a human or animal. To create therapeutic formulation suitable for intravenous administration we need to know the average size and size distribution of nanoparticles, but we don't have adequate technology to do so. This is a critical issue, because cellular uptake of such nanoparticles is size-dependent. Expertise needed We are looking for a university researcher or a team, who has experience and technology of characterization of nanoparticle suspensions, such as size distribution, particle stability and can estimate particle shape. Also we need help in the analysis and interpretation of generated data. Keywords anti-COVID-19 therapeutics
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Organization type Private Sector Province Quebec Challenges We are developing anti-COVID-19 therapeutics based on nanoencapsulated CRISPR-Cas systems programmed to target and selectively destroy the viral genome. At this stage of development we need to run in-vitro and preclinical studies, however we don't have all required expertise and facilities. From our side we provide all our expertise, IP, in-kind and other measures required for a successful project. Expertise needed We are looking for collaboration with university researchers and research groups who are experts in the following: <br>-Plasmid (E.coli) biotechnology, Cas protein expression and purification<br>-RNA synthesis (60-10 nucleotides)<br>-Cellular models of RNA expression;<br>-Animal models, mice, vivarium<br>-PCR and qPCR<br>We are also seeking collaboration with: <br>-researchers who may participate in design of viral models and tests<br>-researchers who are interested in the organization of animal studies and full range clinical studies Keywords anti-COVID-19 therapeutics
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Organization type Private Sector Province Ontario Challenges [The product] is the first A.I. assistant for residential property managers in North America. [The product] works solely by SMS text-message, with no apps or software needed. Our mission: [The product] was created by two former property managers with more than 15 years of industry experience. In response to COVID-19, our mission is to promote safe living in residential communities by providing virtual automated property management. Our business has grown rapidly since the COVID-19 pandemic started. [The product] has grown 10x in the last 60 days, and the growth is expected to continue. While much of the focus during the COVID-19 pandemic is medical research and PPE manufacturing, our goal is to help Canadians by making the one place, where we all spend most of our time now—our homes—as safe as can be. Residential property management is an essential service. With the current social distancing, self-isolation and lockdown requirements in place across North America, property management companies and residents need a tool for virtual property management that also encourages this safe living and distancing. Our A.I. assistant provides this solution. Property management companies are relying on [the product] to handle the increased number of resident inquiries, text health updates to residents, coordinate contactless food deliveries, and fill in labour gaps caused by site staff layoffs. Many of our clients are changing the way they manage properties, and they are relying on [the product] to automate operations remotely. In addition to the tasks mentioned above, here are some more functions it can do for clients: <br>• Coordinate contactless deliveries <br>• Issue virtual fobs to provide access to buildings <br>• Schedule and facilitate digital tours of properties<br>• Manage payments and answer account questions <br>• Issue and track service requests <br>• Schedule moves and inspections<br>• Book amenities and elevators <br>• Start digital forms <br>• Communicate virtually <br>• and much more! Expertise needed In order to achieve our property management automation goals, the following technical IP needs to be further developed: <br> • Real-time Annotatorb<br>We will focus on developing a real-time annotation and training dashboard that allows human-in-the-loop training of user inquiry data in real time. This also includes the expansion of our Natural Language Processor. By creating a platform to quickly classify and train data, we can increase confidence levels for automatic answering and responding to more questions, allowing us to achieve our automation objectives. <br>• Enhanced Database Management System<br>This includes further developing the platform that allows for the creation and training of curated data sets, building management, confusion analysis, machine learning and connection to third party APIs. This will help us improve our automation accuracy out of the box for new clients, allowing for enhanced automation tasks. Keywords property management, artificial intelligence
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Organization type Private Sector Province Ontario Challenges My company is working on providing affordable, sustainable and natural food with a long shelf life and enhanced natural vitamins—especially vitamin C and vitamin K2—through fermentation. Our aim is to save the environment, prevent food waste and provide affordable nutrition, especially during periods of lockdown, as in the COVID-19 pandemic, when obtaining fresh food is difficult or pricey and when building a strong immune system in the body helps to reduce the impact of a disease on the society. Also, it is our goal to provide essential compact food for the sick people at home with diminished appetite to enhance their recovery. <br> Objectives: Developing new food combining nutraceutical ingredients to preserve certain level of vitamins in the final product. Expertise needed Lab with expertise and equipment to measure vitamin content of food. Lab with expertise and equipment, including freeze drying machine for developing the new food. Keywords natural food, vitamins, nutraceutical
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Organization type Private Sector Province British Columbia Challenges The organization has been building autonomous ground vehicles for turf management, logistics and agriculture. The organization’s robots can operate safely around humans (detection and stopping) with sub-centimeter positional accuracy. The organization is applying its expertise towards the design and building of: <br>• a high volume UVC sterilization robot, and <br>• an equipment sterilization chamber. <br>The applications of these instruments are for sterilization of N95 masks, hospital rooms, seniors’ homes, airports, supermarkets, vegetables, etc. The organization would like to partner with a university research team to help study the efficacy of The organization's UVC robot and chamber for disinfecting virus and or bacterial contamination of surfaces, N95 masks and gowns, and air. The study would involve UVC time and intensity requirements to achieve a 99.9% decontamination results. The study would involve different bacteria and viruses. The study would look at N95 material degradation vs. UVC time and intensity. Expertise needed The organization would like to partner with a local university who works with the local hospitals on infectious control to help effectuate the research into efficacy for decontaminating different bacterial/virus strains, for different surfaces and materials (cloths, plastics). Examples of bacteria to study: <br>• Staphylococcus aureus<br>• Pseudomonas aeruginosa<br>• Clostridium botulinum<br>• Escherichia coli<br>Examples of viruses to study: <br>• SARS-CoV2 <br>• Influenza A <br>• Human Rhinovirus <br>Depending on guidance from Health Canada and laboratory bio-safety requirements, the organization will choose the appropriate bacteria and viruses. Keywords autonomous robotics, UVC sterilizer
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Organization type Private Sector Province Ontario Challenges The organization has proprietary technology based on Picosecond Infrared Laser – Desorption by Impulsive Vibrational Excitation – Mass Spectrometry (PIRL-DIVE-MS). We have the capability of injecting entire viruses into the gas phase fully intact with near 100% collection efficiency. COVID-19 has a mass in the range of 600 MDa with approximately 150 surface charges (M/Z of approx. 1 MDa). No healthy person should have 600 MDa particles in their mucosal fluids. Typical viral loads are 10^6 to 10^9 virus/ml for sick individuals, which should be well in the detection capabilities of PIRL-DIVE-MS. The sampling rate is only limited by moving of a spotted plate with either swab heads or solution extracted swab material. We have the prospect of being able to do 36,000 tests per hour with a single instrument. This testing rate is the fastest possible—only limited by motion of high speed stations (and robotic loading of plates, which would be done in a highly parallelized manner). At this sampling rate, a single instrument could test an entire city within a single day for real-time localization of any viral spread and containment of the virus. This ability of high-speed testing is what is needed to fully localize and contain the virus. Moreover, PIRL-DIVE-MS is a universal tool that would be ready for the next pandemic. Expertise needed The challenge is the detector for viral detection. We don't know the sensitivity of current generation of detectors nor the charge to mass ratio of the virus that may allow relatively sensitive detection. There have only been a few papers using MS to directly detect viruses. The problem in the past has been collection efficiency and fragmentation of viruses. With PIRL-DIVE-MS, collection efficiency is solved; however we have no data on overall detection efficiency. We need proof of principle experiments to show that viruses can be directly detected with MS and the sensitivity limits to compare to current gold standard RNA/Reverse transcriptase/PCR tests. It is important to realize that PIRL-DIVE-MS involves no mechanical handling of samples, solvents (other than initial extraction if needed) or waiting times for chemical amplification. This is the fastest test possible. Issues of accuracy in detecting a particular virus is the next phase but we expect this MS assignment to be unique as each virus has a unique shape and should have corresponding unique masses. Keywords direct virus detection with MS, PIRL-DIVE-MS
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Organization type Private Sector Province Alberta Challenges Our organization requires the evaluation of various nanoparticle/polymer-based filtration materials as alternatives to traditional polypropylene-based N95 respirators. Specific objectives include: <br> - Designing a nanofiber composite with 95% particulate filtration efficiency, in accordance with NIOSH regulatory standards <br>- Evaluating the filtration efficiency and resistance at initial penetration of experimental nanofiber composites <br>- Determining the scaleability of a given nanofiber material to an annual production rate of 50,000 m2 Expertise needed We are in need of researchers with expertise in materials and/or nanoscale systems engineering in order to establish a theoretical framework, and subsequently conduct a proof of concept study in line with the objectives outlined above. A potential approach may involve evaluating the particulate filtration efficiency of electrospun 16CA-60 min (cellulose acetate DMA/c (2:1 v/v)), or modified, nanoparticle/polymer soaked KimTech industrial wipes. The details of the experimental approach will be left to the principal investigator’s discretion. Keywords filtration material, N95 respirator, nanofiber
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Organization type Private Sector Province Ontario Challenges The organization has extensive experience in developing and deploying technology solutions at a local and regional level in Ontario, Quebec, New-Brunswick, Nova Scotia and Newfoundland. Our clients include large acute care facilities, community hospitals and rehabilitation centers serving hundreds of thousands of patients every year. COVID-19 has significantly impacted our users, physicians and clinical staff. There is a major need to improve and optimize infection prevention, contact tracing and infection control in our Canadian healthcare. The proposed infection surveillance and management project seeks to make available to Canadian healthcare systems and long-term care facilities a new and powerful infection prevention and surveillance software solution that will help them better cope with the current situation and be prepared for a future pandemic. The solution will enable physicians, nurses, allied health and infection control professionals to make better data-driven decisions while reducing costs. Our projects objectives are as follows: <br> - Design and develop a solution that empowers staff in hospitals, rehab and long-term care facilities, to prevent, manage and track COVID-19 and other viral infections using latest technology <br>-Collaborate with academia partners for expertise, insight, input and confirmation of key features and functionality<br>-Validate newly developed solutions/approaches with our clients <br>-Create a software solution that can be piloted with Canadian healthcare organizations Expertise needed We need to access and work closely with infection control clinical experts, as well as people with experience in applied research with highly qualified personnel (HQP) training (students), data engineering, modelling and simulation, machine learning and neural networks for big data analysis either in cloud, or internet of things (IoT). We are also seeking partners with expertise in data warehousing and data mining. We plan to conduct beta trials with Canadian hospitals before releasing it commercially. Keywords healthcare IT, infection management
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